Category: DNA

Antibody attributes that predict the neutralization and effector function of polyclonal responses to SARS-CoV-2

While antibodies can provide significant protection from SARS-CoV-2 infection and disease sequelae, the specific attributes of the humoral response that contribute to immunity are incompletely defined.  We employ machine learning to relate characteristics of the polyclonal antibody response raised by natural...

The porcine translational research database: a manually curated, genomics and proteomics-based research resource.

The use of swine in biomedical research has increased considerably over the last decade. Various genomic and proteomic databases have been developed to facilitate research with human models and rodents. The databases of current swine genes, however, lack the robust annotation...

LeptoDB: an integrated database of genomics and proteomics resource of Leptospira.

Leptospirose is a potentially fatal zoo-anthroponosis caused by Laptipira’s pathogenic species belonging to Leptospiraceae’s family, with a global distribution and effect, in terms of burden and risk for human health. The “leptob” is a single window dedicated architecture (5,948,311 entries), modeled...

Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics.

The multiplexed quantitative analyzes of complex proteomas allow deep biological insight. Although a multitude of workflow has been developed for multiplexed analyzes, the most accurate quantitative method (SPS-MS3) suffers from long acquisition cycles. We have built a new real-time database search...

ILDGDB: a manually curated database of genomics, transcriptomics, proteomics and drug information for interstitial lung diseases

Interstitial pulmonary diseases (ILDs), a diverse group of diffuse pulmonary diseases mainly affect pulmonary parenchyma. “OMICS” low-flow “OMICS” technologies (genomics, transcriptomic, proteomics) and relative medications have begun to reshape our understanding of ILLD, while these data are dispersed between massive references...

Detailed tail proteomic analysis of axolotl (Ambystoma mexicanum) using an mRNA-seq reference database.

Salamander Axolotl is emerging as an important model for stem cell research because of its powerful regeneration capacity. Several advantages, such as the strong capacity for regeneration of advanced tissues, organs and appendices, promote Axolotl as an ideal model system to...