While antibodies can provide significant protection from SARS-CoV-2 infection and disease sequelae, the specific attributes of the humoral response that contribute to immunity are incompletely defined. We employ machine learning to relate characteristics of the polyclonal antibody response raised by natural...
The use of swine in biomedical research has increased considerably over the last decade. Various genomic and proteomic databases have been developed to facilitate research with human models and rodents. The databases of current swine genes, however, lack the robust annotation...
Leptospirose is a potentially fatal zoo-anthroponosis caused by Laptipira’s pathogenic species belonging to Leptospiraceae’s family, with a global distribution and effect, in terms of burden and risk for human health. The “leptob” is a single window dedicated architecture (5,948,311 entries), modeled...
The multiplexed quantitative analyzes of complex proteomas allow deep biological insight. Although a multitude of workflow has been developed for multiplexed analyzes, the most accurate quantitative method (SPS-MS3) suffers from long acquisition cycles. We have built a new real-time database search...
Interstitial pulmonary diseases (ILDs), a diverse group of diffuse pulmonary diseases mainly affect pulmonary parenchyma. “OMICS” low-flow “OMICS” technologies (genomics, transcriptomic, proteomics) and relative medications have begun to reshape our understanding of ILLD, while these data are dispersed between massive references...
Salamander Axolotl is emerging as an important model for stem cell research because of its powerful regeneration capacity. Several advantages, such as the strong capacity for regeneration of advanced tissues, organs and appendices, promote Axolotl as an ideal model system to...